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as in the case of the elevated mRNA, the basal bioavailable selenium may become the limiting factor for the efficient translation, whereas in the case of the elevated bioavailable selenium, the basal mRNA levels of seleno-GPxs may become the limiting factor for the overall increase of the protein activity
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The term cytochrome P450 is derived from the original observation that these enzymes, isolated from hepatocyte ER microsomes, are chemically similar to mitochondrial cytochromes, and are reddish in pigmentation reflecting the heme that is part of their molecular structure
10.1530/EC-19-0557 13 dos Santos RibeiroH
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