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Multiple CVB variants have been shown to induce cell degeneration, pyknosis, reduction of islet identity genes, and decreased insulin content and secretion in primary human islets cultured in vitro or transplanted into diabetic NOD mice (141, 143)

Disease Prevention Cardiovascular disease Interest in garlic and its potential to prevent cardiovascular disease began with observations that people living near the Mediterranean basin had lower mortality from cardiovascular disease (88)

Retrieved from Farokhnia, M., McDiarmid, G

These effects typically occur during dose initiation or escalation and often diminish over time as the body adjusts to the medication