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Both medications share comparable safety profiles, with common gastrointestinal side effects including nausea, vomiting, diarrhea, and abdominal pain that are generally mild to moderate and resolve as the body adjusts

Medicare: For Medicare beneficiaries, coverage depends on the prescribed indication: For OSA: Many Medicare Part D and Advantage plans now cover it for this purpose

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Whether this pattern persists beyond 52 weeks, whether it is dose-dependent, and whether it is reversible upon discontinuation of therapy are questions that remain unanswered and need to be addressed in larger, longer-duration trials