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This is evidenced by the negligible affinity of amylin or pramlintide for the isolated CTR ECD 19,20 , and by loss of affinity and/or potency of P32Y substituted CT peptides at the CTR 18,20
Baltruskeviciene, E
Even lower doses showed clinically meaningful results: the 10 mg dose achieved approximately 21% weight loss, and the 5 mg dose produced around 16% weight loss
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