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Follow the advice of your dialysis team on how to monitor changes in your access site that can point to a problem

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However, some peptides, such as semaglutide and tirzepatide, are FDA-approved for weight loss under brand names Wegovy and Zepbound, respectively

The main rationale for cycling rather than continuous use involves conservative safety practices given limited long-term human data, cost management, and theoretical concerns about receptor desensitization with extended exposure