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Caffeine: If using, limit to morning only and track effect on sleep
GLP-1, or Glucagon-like Peptide-1, is a hormone produced in the gut, specifically by the L cells of the small intestine and colon
STEP-5 extended the observation window to 104 weeks (N=304) and found mean weight loss of 15.2% with semaglutide 2.4 mg versus 2.6% placebo, demonstrating that the drug sustains its effect across two full years without clinically meaningful attenuation [10]
Why GLP-1 Medications Pose a Unique Challenge During Lactation GLP-1 receptor agonists work by binding to receptors throughout the bodyincluding in the gastrointestinal tract and central nervous system
