According to FDA prescribing information, these include nausea (occurring in 1544% of patients depending on the agent and dose), vomiting, diarrhea, constipation, and abdominal pain
They disrupt fundamental cellular processes, including energy production, insulin signaling, glucose metabolism, and mitochondrial function, at times contributing to cognitive decline, fatigue, reduced ability to fight infections, and increased chronic disease risk
PMC / Cureus
Some people may experience: Mild digestive upset if taken on an empty stomach Rare allergic reactions Temporary skin lightening (which is often the desired effect) Its always recommended to start with a lower dose and consult with a healthcare professional before beginning any new supplement regimen