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Another source of deficiency can be malabsorption issues, where the body is unable to properly absorb B12 from the intestines due to various gastrointestinal disorders
Consistently, an indirect inhibition of intestinal FXR through microbiota modulation, or genetic deletion of intestinal FXR, corroborate this phenome displaying protection from high-fat diets induced obesity and fatty liver disease (351)
This underdosing concern is something anyone evaluating probiotic and prebiotic GLP-1 supplements should understand
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