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Treatments are usually spaced around a week apart, but your provider will tailor your treatment plan based on your symptoms and response

In this same population there was a non-statistically significant increase in DVT and stroke in the patients randomized to tamoxifen

It should also be noted that, from a methodological perspective, the model used (Cox with stratification by cardiovascular risk class of the trials, i.e., SURPASS-4: high risk, and all others: low risk) requires various assumptions, including the homogeneity of the relative effect of tirzepatide treatment on MACE regardless of the baseline cardiovascular risk level of the patients

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