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Preserved glucagon-like peptide-1 responses to oral glucose, but reduced incretin effect, insulin secretion and sensitivity in young asians with type 2 diabetes mellitus
The anti-inflammatory pharmacology of pycnogenol in humans involves COX-2 and 5-LOX mRNA expression in leukocytes
For example, after a 12-week cycle, a 4- to 6-week break is often sufficient for biomarkers to normalize
However, due to limited human clinical trials, long-term safety is not fully understood
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