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Plasmodium falciparum Sir2 is an NAD+-dependent deacetylase and an [PMID: 18729382] Laboratory literature summary: Plasmodium falciparum Sir2 is an NAD+-dependent deacetylase and an acetyllysine-dependent and acetyllysine-independent NAD+ glycohydrolase
Phase 2 studies showed therapeutic levels could be achieved in patients
Synaptogenesis & dendritic spines Investigated in rodent tissue and cell models for its reported ability to increase dendritic spine density preclinical only, and the primary source assays were retracted in 2025
[7] Finkley et al
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