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We next examined the p K a values of the five cysteines: C8, C23, C26, C79, and C83, as cysteine thiol deprotonation is a critical step for subsequent glutathionylation or oxidation by H 2 O 2 32

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Practical takeaway: If your real goal is weight or metabolic health, the most useful next step is discussing approved treatment options with a clinician rather than relying on an unapproved compound

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