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For context, the Phase 2 study (Jastreboff 2023, NEJM) reported about 17.5 percent mean weight reduction at 24 weeks on 12 mg
Because these products are classified as food supplements rather than medicines, manufacturers are not required to prove purity, potency, or safety before sale
It also matters for accuracy at high doses, because you can fit the entire dose within a 1 ml syringe up to 20 mg
It works through antihistamine pathways rather than serotonin blockade
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