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Its continued use in laboratory investigations has contributed to a substantial body of research focused on peptide-mediated signalling mechanisms
Indeed, data from STEP-HFpEF and STEP-HFpEF DM trials have shown a significant reduction in inflammatory markers such as CRP with semaglutide compared with placebo 45,46
doi: 10.2337/diacare.28.5.1092 214 GujaCFrasJPSomogyiAJabbourSWangHHardyEet al
In a sensitivity analysis, we constructed cohorts in which each participant could only contribute with one treatment episode
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