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Monitoring Thyroid Function During GLP-1 Treatment Patients taking both levothyroxine and semaglutide should establish a baseline TSH level before starting GLP-1 therapy and recheck it 6 to 8 weeks after initiation

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The five high-resolution cryo-EM structures reported here, together with abundant structural and pharmacological data of monospecific peptides documented previously 4,25,27,30,40 , provide us an excellent opportunity to analyze the molecular basis of the superior clinical efficacy presented by multi-targeting agonists

Boyd RJ, Avramopoulos D, Jantzie LL, McCallion AS