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A population pharmacokinetic model developed using data from clinical trials of subcutaneous and intravenous semaglutide was modified to include data from six trials of oral semaglutide in healthy volunteers or patients with T2D and renal or hepatic impairment [66, 67]
Oral Contraceptive Pills Clinically Critical Both tirzepatide and semaglutide reduce the peak plasma concentration of oral contraceptive pills by slowing gastric absorption, potentially reducing their effectiveness
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