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If the agency formally removes GLP-1 drugs from its shortage list, the regulatory pathway that has fueled the companys rapid expansion into the weight loss space to this point will become less straightforward, forcing a reckoning with its business model and strategy
Five receptors, four endogenous ligands, three reference synthetic analogs (MT-II, PT-141, afamelanotide) and two regulatory approvals (Scenesse, Vyleesi) cover a spectrum ranging from pigmentation to sexual function, via energy homeostasis and sebaceous exocytosis
In the 12mg cohort, 83% of participants achieved at least 15% weight loss, and more than half exceeded 25%
glucose tolerance test (IPGTT) or plasma glucose during ad libitum (AL) feeding (Extended Data Fig
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