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doi: 10.1186/s12902-020-00563-y 66 LiuTLiuC-AZhangQ-SZhangQWangY-MSongM-Met al
Symptoms of pernicious anemia High serum folate levels Serum folate is the level of folic acid in the blood
The most common gastrointestinal symptoms include: Nausea (1220% of patients): Usually mild to moderate, most pronounced 13 days after injection, typically improving within the first month Diarrhea (716% of patients): Often resolves as the body adjusts to the medication Decreased appetite : An expected pharmacologic effect that contributes to weight loss Constipation (57% of patients): May require dietary fiber adjustments or stool softeners Vomiting (28% of patients): Less common but warrants medical attention if persistent Abdominal discomfort or bloating : Related to delayed gastric emptying Most gastrointestinal side effects are mild to moderate in severity and diminish significantly after 48 weeks as tolerance develops
Similarly, body mass index (BMI) can guide dosing decisions patients with higher BMIs may need larger maintenance doses to achieve effective weight loss
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