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The combination of GLP-1, GIP and/or GCG agonist actions with amylinthrough the incorporation of cagrisemaglutide or amicretinopens the door to the development of new multiagonists as treatments for obesity, type 2 diabetes, and possibly other chronic diseases

Clinical data from the STEP trials shows clear dose-dependent increases in side effects

Caffeine can be thought of as a middleman

DWI was acquired as a single-shot echo-planar imaging (EPI) sequence with field of view (FOV) 480480 mm 2 , resolution 3.04.757 mm 3 , echo time (TE) 50.6 ms, repetition time (TR) 4000 ms, matrix 256256, slice thickness 7 mm, and b-values 50 s/mm 2 and 800 s/mm 2 , during breath-hold at end-expiration