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This selectivity makes FOXO4-DRI valuable for tissue engineering applications where elimination of senescent cells from expanded cell populations could improve research outcomes and provide researchers with enhanced cell preparation methods for regenerative medicine investigations

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Second, the development of new drugs requires additional and more detailed preclinical and clinical studies to determine whether long-term use is biotoxic, whether the drug has adverse effects on other peripheral organs or whether the drug candidate has a real therapeutic effect on the patients

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