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Cagrilintide (Cagri), functioning as a dual amylin receptor (AMYRs) and calcitonin receptor (CTR) agonist (DACRA), demonstrates significant efficacy in obesity treatment, although its structural activation mechanism remains unclear
Hypothyroidism can result from an autoimmune condition known as Hashimoto's disease , a disease in which the immune system attacks the thyroid gland and prevents it from making enough hormones
Glucagon historically raises blood glucose, which is why its role in an anti-obesity drug seems counterintuitive
& Dumontet, C
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