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Macrophages contain brown lipofuscin and lysosomal debris

In the DURATION program for type 2 diabetes: DURATION-1 : Exenatide ER (Bydureon) 2 mg weekly produced 3.7 kg weight loss over 30 weeks DURATION-5 : Bydureon produced 2.3 kg weight loss over 24 weeks Three-year data : Sustained weight reduction of approximately 2.3 kg (5.1 lbs) from baseline Exenatide is not FDA-approved for chronic weight management

This medication is also not advised for people with an allergy to any of the components in the solution.

Researchers combining these compounds should start with conservative doses of each and monitor closely for unexpected effects