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The biased agonism is a real feature of the molecule, not an artifact, and contributes to a pharmacological profile distinct from balanced dual agonists or pure GLP-1 mono-agonists
It is a dual agonist of GLP-1 and GIP receptors to help regulate blood sugar levels and reduce appetite to improve glycemic control and support weight loss in patients with chronic conditions
When Pinto has a patient who asks about weaning off their GLP-1 or spacing out dosing, he is very receptive to the conversation
And in rare cases, a reaction signals something that genuinely needs medical attention
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