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Nausea, vomiting, and other gastrointestinal symptoms are common, particularly when starting or increasing the dose and in T1D trials, these rates were similar to those seen in T2D and obesity trials
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One such specialized group of enzymes called Glutathione-S-Transferase (GST) attach glutathione to the byproducts of Phase 1 detoxification and neutralizes their toxic potential while simultaneously making these toxic substances more water-soluble and ready to be eliminated
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