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Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice
The most frequently reported adverse events were gastrointestinal events, including nausea, vomiting, diarrhea, constipation, or abdominal pain, which affected 79.6% of participants in the cagrilintide-semaglutide group and 39.9% of those in the placebo group
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