semaglutide versus glp-1 & tirzepatide are transforming diabetes & obesity management. These receptor agonists offer benefits from glycemic control to weight loss and cardiovascular risk reduction, emphasizing their broad impact. Read more from What are GLP-1 drugs? The

Neumiller JJ, Sonnett TE, Wood LD, et al

In a randomized trial of semaglutide 2.4 mg vs placebo for 1 year, 529 participants with HFpEF with a BMI of 30 kg/m2, there was a very large reduction in symptoms, improvement in exercise function in the GLP-1 drug assigned group

Adults with SPCD must still avoid prolonged fastingwhich generally means skipping meals during the day, fasting for religious reasons, or fasting prior to medical procedures/bloodworkand must take their prescribed L-carnitine consistently to avoid muscle breakdown ( rhabdomyolysis ) and other complications [10] [6]

Carnitine: a therapeutic option for childhood psoriatic onycho-pachydermo-periostitis (POPP)