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SCFAs activate GPCRs (GPR43/41) and inhibit histone deacetylases (HDAC), promoting regulatory T-cell (Treg) differentiation while suppressing Th17 cell polarization within the joint, thereby restoring immune homeostasis and reducing pro-inflammatory cytokine release
L., Chen, C
Moreover, it would be beneficial for future studies to investigate additional markers in order to provide data related to a wider spectrum of oxidative stress and redox status
Consistency with supplementation and addressing any underlying health issues are crucial for maximizing the benefits of B12 injections
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