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GLP-1 directly stimulates POMC/CART neurons and indirectly inhibits neuropeptide Y (NPY) and agouti-related peptide (AgRP) to increase measures of satiety and decrease hunger [32]
That's why the weight comes back when the drug stops
All serious risks are significantly reduced by appropriate medical supervision and clinical-grade formulations
doi:10.1016/j.molmet.2019.09.010 Crosby Lee , Davis Brenda , Joshi Shivam , Jardine Meghan , Paul Jennifer , Neola Maggie , Barnard Neal D
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