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Rho kinase mediates Porphyromonas gingivalis outer membrane vesicle-induced suppression of endothelial nitric oxide synthase through ERK1/2 and p38 MAPK

Experimental data indicate increased functional tone of the lower esophageal and pyloric sphincters following peptide administration, a response associated with reduced reflux-related injury and attenuation of esophageal inflammation in animal models (11)

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B-12 also plays a crucial role in the production of red blood cells, helping to prevent anemia