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Other Reported Adverse Effects In addition to gastrointestinal issues and thyroid-related risks, semaglutide may cause other side effects, including: Fatigue and Dizziness : Some individuals report feeling unusually tired or dizzy while taking semaglutide
The glucagon peptide family [glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic peptide (GIP) and glucagon] Figure 2: Simplified schematic overview of the glucagon superfamily of peptides [28] The glucagon peptide family members [GLP-1, GIP and glucagon] have similar peptide sequences, permitting the development of single-sequence multi-receptor agonists [4]
The STEP trials show that continuing Wegovy maintains weight loss, while stopping leads to a regain of around two-thirds of the weight lost within a year
For those who require maximal weight loss, such as people managing severe obesity alongside cardiovascular risk or obstructive sleep apnoea, injectable therapy may remain the medically preferred route
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