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Feb 24, 2025 TL1 Postdoctoral Training Program Spotlight: Aaron Smith Ph.D., RD, University of Kansas Medical Center Jan 13, 2025 KL2 Scholar, April McNeill-Johnson, M.D., Childrens Mercy Kansas City Jan 10, 2025 Frances M
There is accumulating evidence for diverse changes in molecular expression of reactive astrocytes in different types and different severities of tissue pathology, 62,65,68,69 but there is not yet a good synthesis of how molecular, metabolic, 87 structural, and functional changes relate to one another to generate precisely definable phenotypes
This idea aligns with a broader theory of aging sometimes called epigenetic drift. Over time, cells gradually lose some of their ability to maintain the precise patterns of gene expression that characterize healthy tissue
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