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[16] Biological sources and degradation [edit] Lipoic acid is present in many foods in which it is bound to lysine in proteins, [3] but slightly more so in kidney, heart, liver, spinach, broccoli, and yeast extract
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FoxO1 binds to the GPX 4 gene promoter, stimulating its expression and increasing the antioxidant capacity, thereby suppressing ferroptosis ( tuba3fp , which accelerates ubiquitin-dependent degradation of critical ferroptosis inducers such as IRGQ, further inhibiting ferroptosis ( Figure 2 ) ( 2.2.2 The role of the KRAS signaling pathway in cervical cancer cells resistance to ferroptosis Kirsten rat sarcoma viral oncogene (KRAS) is a member of the RAS gene family, located on the short arm of human chromosome 12 (12p1.1-pter)