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Allergy Asthma Immunol Res
Activation of PARP-1 also leads to decreased NADPH levels because this particular PARP inhibits the glycolytic enzyme, hexokinase
Use In Pregnancy & Lactation Pregnancy: Because of the possibility of hemolytic anemia due to immature erythrocyte enzyme systems (glutathione instability), the drug is contraindicated in pregnant patients at term (38-42 weeks' gestation), during labor and delivery, or when the onset of labor is imminent, because of the possible risk of haemolysis of the infants' immature red cells (see Contraindications)
Allyl isothiocyanate depletes glutathione and upregulates expression of glutathione S-transferases in Arabidopsis thaliana
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