Similar to K cells, L cells also express the Galinin receptor, GAL 1 , and its activation via Galinin treatment or GAL 1 agonist (M617) treatment prevents the accumulation of cyclic adenosine monophosphate (cAMP) in L cells within primary duodenal cultures in response to the adenylyl cyclase activator, forskolin and inhibits GLP-1 secretion from primary duodenal and ileal cultures (Psichas et al., 2016)
This program is only slated to run from July 1st, 2026 through December 31st, 2027
In an advisory published Friday, the department announced seizures of unauthorized injectable peptide drugs, often used for bodybuilding, anti-aging, or enhancing athletic performance
just keep an eye out for additives like sugar alcohols (e.g., sorbitol, xylitol) and sugar substitutes (for instance, monk fruit or stevia), which can spark GI troublesomething you may especially want to avoid, given GLP-1s can trigger digestive side effects too