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It integrates hemodynamic, metabolic, and inflammatory insults through molecular pathways centered around NO deficiency, oxidative stress, and immune activation
the two components most vulnerable to oxidative damage due to increased mass of polyunsaturated fatty acids and respiratory activity in neurons
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371 In a study examining the effects of GLP-1RA on osteoporosis induced by ovariectomy in aged rats, administering exendin-4 for 16 weeks prevented deterioration of the trabecular microarchitecture and increased bone strength
