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A sub-study of this trial focused on GC through the use of continuous glucose monitoring (CGM) and the proportion of time within a tight predefined time in range (TIR) from 71 to 140 mg/dL at the end of the study was considerably more significant in the group of participants receiving either 10 or 15 mg TZP competed to the group taking insulin degludec (72, 73, 75)
It creates a surge of oxidative stress in the gut, disrupting the balance of your microbiome
This mechanism drives weight loss but can trigger nausea, constipation, and reflux in the first weeks of treatment
Clinical data on this specific combination is limited, but the pharmacological rationale is sound
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