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However, total BMC, when adjusted for body weight, remained unchanged

Normally, high-fat diets can lead to thickening and other changes in this tissue layer and rewire how the gut responds to food

doi: 10.1038/s41422-018-0090-y 48

There are other forms of bias in these datasets including channeling (e.g., the prescribing pattern depends on a patient characteristic (particularly diabetes or obesity) that is a PDAC risk factor), detection (e.g., overreporting due to additional testing to rule out a suspected adverse event (e.g., imaging triggered by pancreas enzyme elevations)), and Weber effect (initial increase in event reporting shortly after drug launch) 49