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Our data clearly showed that caspase-dependent apoptosis was specifically induced by CPP-CAND in senescent cells
Non-12-OH FXR-antagonistic BAs mediates the T3 effect on glucose homeostasis To dissect the contribution of the augmentation of non-12-OH FXR-antagonistic BAs to the improved glucose metabolism after T3 daily injection, MMI mice were fed a diet supplemented with TMCA, the most abundant murine FXR-antagonistic BA, for five days
The presence of mycotoxins in the brain can induce or serve as risk factor for the activation of the immune cells (microglial, astrocytes and endothelial cells) through the modulation of toll like receptors (TLRs), and subsequently the activation of different signaling pathways with release of inflammatory cytokines (Tumor necrosis factor- (TNF-), Interleukin-6 (Il-6), Interleukin-1 (Il-1)), nitric oxide synthase (iNOS) and chemokines
Insufficient research on the differences in the effects of SSRIs in different genders and developmental stages (e.g., embryonic, puberty, adulthood)
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