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In regression models that included liver triglyceride concentration and mRNA expression for the GABA shunt enzymes (SSADH and GABA-T) or GABA transporters (Slc6A6, A8, A12, and A13), SSADH mRNA expression was positively associated with 4h fasted serum insulin (P = 0.0013
Clinicians will usually only prescribe these medications like Zepbound, Mounjaro and Ozempic if your body mass index (BMI) is 30 or higher (27 or higher if it's accompanied by weight-related medical conditions such as high blood pressure, heart disease, type 2 diabetes, pre-diabetes, high cholesterol, non-alcoholic fatty liver disease, obstructive sleep apnea or PCOS)
Local clinic timelines depend on availability and wait times
The medication is started low and raised gradually, so meaningful results take time and depend on diet, activity, and consistent use
