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For the hepsin / mice, the timing of mortality was such that it occurred prior the onset of liver repair and regeneration processes, thereby confirming the role of hepsin in determining the mechanism of APAP toxicity tolerance during the early phase of drug exposure
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When the balance of these hormones is disrupted, it can lead to gut disorders such as inflammatory bowel disease and colorectal cancer
Aug 2021;263:72-78
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