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GLP-1 AND DUAL AGONISTS In summary, the research progress of GLP-1 in lipid metabolism shows its potential in the treatment of metabolic disorders such as NAFLD, especially combined with its significant weight loss effect, making the application of GLP-1 in obese patients with NAFLD more worthy of in-depth exploration

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no efficacy endpoint expected

In 2024 semaglutide (Wegovy) became the first weight loss drug to also be approved for the reduction of risk of serious cardiovascular events in patients with cardiovascular (CV) disease and obesity and overweight