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Excellent review of the complexity of entero-endocrine cell biology, discussing gaps in current understanding and highlighting the translational relevance of entero-endocrine cells in the pathophysiology and therapy of metabolic and inflammatory disorders

Many patients cannot tolerate the side effects, and its estimated that within a year, 80 to 90% of individuals who start on these drugs discontinue their usage

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Sleep disturbances affect up to 80% of cirrhosis patients, with insomnia and excessive daytime sleepiness being particularly prevalent