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After careful planning with Dr
He repeatedly starved himself to lose weight, then gained it back by binge eating comfort foods
It acts in muscle, adipose tissue, and liver to turn on a set of genes essential for fatty acid oxidation, including the fatty acid transporters carnitine acyltransferases 1 and 2, the fatty acylCoA dehydrogenases for short, medium, long, and very long acyl chains, and related enzymes
In addition, the possibility to manipulate SLC25A39 and/or to regulate the amount of GSH that enters mitochondria also offers the opportunity to study the importance of mitochondrial GSH in more detail, especially in mitochondria-rich tissues like liver or kidney
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