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doi: 10.1016/j.celrep.2022.111308 89 LeeMLeeSYBaeYS

The large molecules in these drugs arent easily absorbed in the gut, so have to go directly into the body by needle

First, there's the Body Mass Index (BMI) threshold

It is a triple receptor agonist , acting on glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors