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Tirzepatide can help reduce overall body fat, including abdominal fat
The REWIND trial (N=9,901) demonstrated that dulaglutide 1.5 mg reduced major adverse cardiovascular events (MACE) by 12% compared to placebo over a median 5.4-year follow-up (HR 0.88, 95% CI 0.79-0.99) [2]
The differential insulinotropic potency and other physiological effects of GIP and GLP-1 in both healthy individuals and those with T2DM may be linked to their distinct receptors and the downstream G proteins that transmit signals intracellularly
For individuals with a history of sensitive stomachs or acid reflux, this combination requires extra care
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