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Semaglutide works by mimicking the action of the glucagon-like peptide-1 (GLP-1) hormone, which helps regulate appetite and food intake
As of early 2026, the longest documented use of Retatrutide in a controlled clinical setting is 68 weeks
Patients taking semaglutide experienced a 24% decrease in risk of major kidney disease events, including kidney failure, a large decline in kidney function, the need for dialysis or transplant, or death related to kidney or cardiovascular causes
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