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3 Long-term change in (A) glycosylated hemoglobin (HbA1c) and (B) estimated glomerular filtration rate (eGFR) among patients with type 2 diabetes mellitus taking sodium-glucose cotransporter-2 inhibitor (SGLT2i) versus glucagon-like peptide-1 receptor agonist (GLP1-RA) in the inverse probability of treatment weighting-adjusted cohort
They may recommend a dose adjustment, a brief pause followed by restart, or complementary approaches
The semaglutide versus tirzepatide dosage comparison shows that tirzepatide achieves greater weight loss at its maximum dose than semaglutide does at its maximum dose, while potentially being better tolerated because the GIP pathway carries less gastrointestinal burden
the platform and methodology have not been independently confirmed
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