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A study in people with type 2 diabetes taking antidiabetic treatment showed that carnitine supplements were able to significantly lower blood sugar levels, compared to a placebo.[2] Carnitine and metabolism Carnitine has the ability to transport fatty acid molecules across cell membranes to the mitochondria, mainly in the heart and skeletal muscles, aiding in their further oxidation and use by the cells

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16 This approval was based on a randomized, double-blind, placebo-controlled trial of 701 patients inadequately controlled on metformin alone