Based on a price of $499 for 2 mg, Americans making the median household income of $81,604 spend an average of 7.3% of their earnings paying out of pocket for the drug
None asked for proof of BMI, nor did any require that I also show evidence of at least one weight-related ailment, even though the official recommendation for prescribing this type of medication to a person with a BMI of 27 is the presence of one such ailment
While choline does not compete with other nutrients for enterocyte transport, gut microbes can limit its bioavailability ( Escherichia coli , Pseudomonas aeruginosa , and Acinetobacter baumannii , choline uptake is mainly mediated by the BetT transporter, whose expression and transport activity are upregulated by hyperosmotic stress ( Figure 2 )
However, anecdotal reports from clinical practices suggest that many patients achieve meaningful weight loss at doses well below the maximum