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Nanocarriers overcome MDR by bypassing efflux pumps, enhancing tumor penetration, and enabling controlled or combinatorial drug delivery
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Importantly, these effects could be achieved at advanced ages, suggesting that IGF-1R mAbs could represent a promising therapeutic candidate to delay aging
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In rodents, SPNs in the C8-T2 segments innervate primarily the superior cervical and middle cervical-stellate ganglion complex 43,44,45,46,47,48,49 , from which postganglionic neurons innervate the heart, salivary glands and the eyes, among other targets 47,50,51,52
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